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Software for patients and brain regions selection suitable for analysis of connectivity in fMRI
Slavíček, Tomáš ; Lamoš, Martin (referee) ; Jan, Jiří (advisor)
The aim of this thesis is to create an exploratory tool for functional magnetic resonance imaging data, which allows quickly and easily making a selection of persons and areas suitable for group analysis of connectivity. In the first chapters of this work is mentioned history of brain research and comparison of methods used in functional imaging. Next they are discussed the theoretical basis of fMRI methods, such as the formation of BOLD signal, acquisition parameters of MRI images and methods for designing experiments. The following chapter describes in detail the analysis of recorded data from the pre-processing to the interpretation of results. The last chapter of the first part describes problems of group analysis in SPM8 software. The second half of this work is dedicated to the description of developed program from data input to saving the results, including detailed descriptions of key features. In conclusion, there is a chapter characterizing the application of developed program on real data from clinical studies, including the results and evaluation of the usability of program. The program will mainly be used in neuroscience research.
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Influence of the reaction time on neuronal response amplitude after the uncommon stimuli in fMRI images
Klimeš, Filip ; Bartoň, Marek (referee) ; Lamoš, Martin (advisor)
The goal of my bachelor’s thesis is to provide basic idea of the functional magnetic resonance imaging. The theoretical part deals with general principles, methods of measurement and analysis of fMRI data. The partial and also key objective is to design ways of modelling reaction time within the concept of general linear model. The goal of the practical part was to become familiar with SPM toolbox and then to implement designed ways on group data. The implementation was carried out at two levels: preprocessing and analysis of measured data. Preprocessed data were subjected to the first level analysis and second level analysis. Next aim is to evaluate the results of both analysis and thus different approaches to the modelling of reaction time and its influence on neuronal response amplitude after uncommon stimuli in functional magnetic resonance images.
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Effect of type of discrimination task on rate and effectiveness of discrimination learning to avoid aposematic prey in avian predators
Jůnová, Lenka ; Exnerová, Alice (advisor) ; Sedláček, Ondřej (referee)
During the proces of learning to distinguish between edible and inedible prey, predators can encounter different types of prey either sequentially (one at a time) or simultaneously. Sequential as well as simultaneous presentation are used as experimental designs for testing discrimination learning of bird predators in relation to aposematic prey. These tasks can differ in difficulty level for predator which can affect test results; however, rate and effectivity of discrimination learning in sequential and simultaneous tasks have never been experimentally compared. We tested effect of type of discrimination task on effectivity of discrimination learning and memorability of prey discrimination in adults and juveniles great tits (Parus major) in two sequential tasks (regular and random) and one simultaneous task (multiple- choice). The birds learned to discriminate between edible and inedible artificial prey on the first day, and we investigated memorability of prey on the second day. We used colour (alternative red/green) or pattern (alternative dots/stripes) as discrimination cue. Results showed that tits learned to discriminate by colour cue better than by pattern cue. Adult tits learned to discriminate better than juveniles independently on task type. Effect of age and sex was shown in some tasks...
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Influence of the reaction time on neuronal response amplitude after the uncommon stimuli in fMRI images
Klimeš, Filip ; Bartoň, Marek (referee) ; Lamoš, Martin (advisor)
The goal of my bachelor’s thesis is to provide basic idea of the functional magnetic resonance imaging. The theoretical part deals with general principles, methods of measurement and analysis of fMRI data. The partial and also key objective is to design ways of modelling reaction time within the concept of general linear model. The goal of the practical part was to become familiar with SPM toolbox and then to implement designed ways on group data. The implementation was carried out at two levels: preprocessing and analysis of measured data. Preprocessed data were subjected to the first level analysis and second level analysis. Next aim is to evaluate the results of both analysis and thus different approaches to the modelling of reaction time and its influence on neuronal response amplitude after uncommon stimuli in functional magnetic resonance images.
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Software for patients and brain regions selection suitable for analysis of connectivity in fMRI
Slavíček, Tomáš ; Lamoš, Martin (referee) ; Jan, Jiří (advisor)
The aim of this thesis is to create an exploratory tool for functional magnetic resonance imaging data, which allows quickly and easily making a selection of persons and areas suitable for group analysis of connectivity. In the first chapters of this work is mentioned history of brain research and comparison of methods used in functional imaging. Next they are discussed the theoretical basis of fMRI methods, such as the formation of BOLD signal, acquisition parameters of MRI images and methods for designing experiments. The following chapter describes in detail the analysis of recorded data from the pre-processing to the interpretation of results. The last chapter of the first part describes problems of group analysis in SPM8 software. The second half of this work is dedicated to the description of developed program from data input to saving the results, including detailed descriptions of key features. In conclusion, there is a chapter characterizing the application of developed program on real data from clinical studies, including the results and evaluation of the usability of program. The program will mainly be used in neuroscience research.
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